Despite the War: Israel’s Biotechnology Investment Landscape Shows Resilience and Innovation in 2024

Israel's health-tech sector secured $1.2 billion in funding in 2024, with digital health leading at $545 million. Major investors such as OrbiMed and OurCrowd drive innovation across biopharma, medical devices, and AI. Despite challenges for early-stage startups, the ecosystem is maturing, attracting global attention according to a report published by Yael Pomerantz, PhD, Health Tech Sector Lead, Startup Nation Central.

Israel’s biotechnology and health-tech ecosystem continues to thrive, as highlighted in the Health Tech Map 2024 report by Startup Nation Central. With $1.2 billion in private funding secured this year, the nation reaffirms its role as a global leader in health-tech innovation. While funding declined from $1.6 billion in 2023, the average deal size surged to $4.6 million, doubling last year’s $2.16 million median. This shift signals a maturing ecosystem that balances later-stage investments with emerging innovation.

Digital Health: The Dominant Sector

Digital health leads the charge, capturing $545 million in investments. Companies in this space are redefining healthcare delivery with cutting-edge AI, telemedicine, and personalized medicine technologies. Top players include:

  • Insightec, which raised $150 million for its MRI-guided focused ultrasound technology.
  • VI Labs, securing $111 million for AI-powered healthcare solutions.
  • AISAP, an early-stage startup raising $13 million for AI-driven ultrasound development.

Medical Devices: A Foundation of Growth

The medical devices sector attracted $380 million, maintaining its position as a cornerstone of Israel’s health-tech ecosystem. Innovations in wearable health monitors, minimally invasive tools, and implantable devices are addressing critical healthcare needs worldwide.Key contributors include:

  • Magenta Medical, receiving $105 million to revolutionize heart failure treatment.
  • Additional startups focusing on surgical precision and chronic disease management, enhancing global healthcare capabilities.

Biopharma: Resilience in Research

Despite global challenges, Israeli biopharma companies secured $262 million, demonstrating their strength in developing next-generation therapeutics. These efforts focus on oncology, neurodegenerative diseases, and genomic medicine.Notable companies:

  • Exsilio Therapeutics, raising $82 million for genomic medicine breakthroughs.
  • Promise Bio, an early-stage startup securing $8.3 million for precision medicine innovation.

Biggest Investors: Driving Israel’s Health-Tech Success

A key component of Israel’s health-tech boom is the support from prominent investors who fuel innovation and growth. Leading investors include:

  • OrbiMed: With $18B in assets under management, OrbiMed focuses on growth and late-stage investments.
  • OurCrowd: Managing $2.35B, it invests across all stages, providing strategic guidance and funding.
  • Vertex Ventures Israel: With $1.6B in assets, this firm targets early-stage health-tech companies.
  • NFX Capital: Specializing in seed and early-stage funding, NFX manages $1B.
  • Entrée Capital: This investor oversees $1.3B in assets, investing $250K to $18M per deal.

These investors play a pivotal role in guiding startups through regulatory hurdles and scaling globally, ensuring the ecosystem’s continued resilience.

Emerging Technologies: AI and Robotics

Artificial intelligence and robotics are transforming health-tech, and Israeli startups are leading the charge. Innovations include robotic-assisted surgery, AI-powered diagnostics, and automated laboratory processes. These technologies promise to redefine efficiency and effectiveness in global healthcare systems.

Economic Insights and Future Outlook

While early-stage startups face challenges in attracting funding, the rise in later-stage investments and strategic partnerships highlights the sector’s maturity. Israel’s health-tech ecosystem continues to attract multinational corporations and international investors, reinforcing its reputation as a hub of innovation.

The Health Tech Map 2024 report underscores the dynamic nature of Israel’s biotechnology sector. With advancements across digital health, medical devices, biopharma, and emerging technologies, the country remains steadfast in shaping the future of global healthcare.